PFKM 抗体 (AA 746-776)
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北京 101111
Quick Overview for PFKM 抗体 (AA 746-776) (ABIN7876723)
抗原
See all PFKM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 746-776
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原理
- PFKM Antibody / Fructose 6 Phosphate Kinase
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纯化方法
- Purified
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免疫原
- A portion of amino acids 746-776 from the human protein was used as the immunogen for the PFKM antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the PFKM antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the PFKM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PFKM (phosphofructokinase, Muscle (PFKM))
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别名
- PFKM
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背景
- Phosphofructokinase catalyzes the irreversible conversion of fructose 6 phosphate to fructose 1,6 bisphosphate. Mammalian PFK is a complex isozyme consisting of 3 subunits: muscle (M), liver (L), and platelet (P). Only M type PFK isozyme is expressed in mature muscle, while erythrocytes contain both L and M subunits. Defects in PFKM are the cause of glycogen storage disease type 7 (GSD7), also known as Tarui disease.
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UniProt
- P08237
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途径
- Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Warburg Effect
抗原
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