GZMB 抗体 (AA 73-187)
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北京 101111
Quick Overview for GZMB 抗体 (AA 73-187) (ABIN7876666)
抗原
See all GZMB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 73-187
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原理
- Granzyme B Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- Amino acids 73-187 were used as the immunogen for the Granzyme B antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the Granzyme B antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Granzyme B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- GZMB (Granzyme B (GZMB))
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别名
- Granzyme B
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背景
- This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. [UniProt]
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UniProt
- P10144
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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