Recombinant GZMB 抗体 (AA 73-187)
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Quick Overview for Recombinant GZMB 抗体 (AA 73-187) (ABIN7876654)
抗原
See all GZMB 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 73-187
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原理
- Recombinant GZMB Antibody / Granzyme B (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 73-187 was used as the immunogen for the recombinant GZMB antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the recombinant GZMB antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant GZMB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GZMB (Granzyme B (GZMB))
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别名
- GZMB
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背景
- Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin s Disease.
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UniProt
- P10144
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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