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Recombinant GZMB 抗体 (AA 73-187)

The 小鼠 单克隆 anti-GZMB antibody (Clone rGZMB-6740) (ABIN7876654) specifically detects GZMB in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7876654
发货至: 中国
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Quick Overview for Recombinant GZMB 抗体 (AA 73-187) (ABIN7876654)

抗原

See all GZMB 抗体
GZMB (Granzyme B (GZMB))

抗体类型

Recombinant Antibody

适用

  • 196
  • 50
  • 25
  • 12
  • 4
  • 4
  • 3
  • 1
  • 1

宿主

  • 107
  • 95
  • 4
小鼠

克隆类型

  • 122
  • 84
单克隆

标记

  • 112
  • 17
  • 11
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GZMB antibody is un-conjugated

应用范围

  • 97
  • 76
  • 46
  • 44
  • 37
  • 29
  • 29
  • 18
  • 18
  • 14
  • 13
  • 10
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

RGZMB-6740
  • 抗原表位

    • 49
    • 17
    • 16
    • 13
    • 11
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 73-187

    原理

    Recombinant GZMB Antibody / Granzyme B (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 73-187 was used as the immunogen for the recombinant GZMB antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the recombinant GZMB antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant GZMB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    GZMB (Granzyme B (GZMB))

    别名

    GZMB

    背景

    Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin s Disease.

    UniProt

    P10144

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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