Recombinant ACE2 抗体 (AA 705-805)
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Quick Overview for Recombinant ACE2 抗体 (AA 705-805) (ABIN7876592)
抗原
See all ACE2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 705-805
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原理
- Angiotensin Converting Enzyme 2 Antibody / ACE2
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 705-805) from the human protein was used as the immunogen for the Angiotensin Converting Enzyme 2 antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the Angiotensin Converting Enzyme 2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Angiotensin Converting Enzyme 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
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别名
- Angiotensin Converting Enzyme 2
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背景
- Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II toangiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage ofangiotensin II, may be an important regulator of heart function. By cleavage of angiotensin II, may also have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SL6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
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UniProt
- Q9BYF1
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途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
抗原
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