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Recombinant ACE2 抗体 (AA 705-805)

This 兔 单克隆 antibody specifically detects ACE2 in ELISA 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7876592
发货至: 中国
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Quick Overview for Recombinant ACE2 抗体 (AA 705-805) (ABIN7876592)

抗原

See all ACE2 抗体
ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This ACE2 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

ACE2-8748R
  • 抗原表位

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    AA 705-805

    原理

    Angiotensin Converting Enzyme 2 Antibody / ACE2

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 705-805) from the human protein was used as the immunogen for the Angiotensin Converting Enzyme 2 antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the Angiotensin Converting Enzyme 2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Angiotensin Converting Enzyme 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

    别名

    Angiotensin Converting Enzyme 2

    背景

    Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II toangiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. By cleavage ofangiotensin II, may be an important regulator of heart function. By cleavage of angiotensin II, may also have a protective role in acute lung injury. Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SL6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.

    UniProt

    Q9BYF1

    途径

    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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