Recombinant RRM1 抗体 (AA 700-800)
Our Local Distributor
北京 101111
Quick Overview for Recombinant RRM1 抗体 (AA 700-800) (ABIN7876550)
抗原
See all RRM1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 700-800
-
原理
- RRM1 Antibody / Ribonucleotide Reductase M1
-
纯化方法
- Protein A/G affinity
-
免疫原
- A portion of amino acids 700-800 of human RRM1 was used as the immunogen for the RRM1 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the RRM1 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.2 mg/mL
-
缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the RRM1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- RRM1 (Ribonucleotide Reductase M1 (RRM1))
-
别名
- RRM1
-
背景
- Ribonucleotide reductase M1 polypeptide (RRM1) is one of two non-identical subunits for ribonucleoside-diphosphate reductase, an enzyme which catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RRM1 is present throughout the cell division cycle but downregulated in quiescent cells. RRM1 is involved in carcinogenesis, tumor progression, and the response of non-small-cell lung cancer (NSCLC) to chemotherapy.
-
UniProt
- P23921
-
途径
- Positive Regulation of Endopeptidase Activity
抗原
-