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RRM1 抗体 (Center)

RRM1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854856
发货至: 中国
  • 抗原 See all RRM1 抗体
    RRM1 (Ribonucleotide Reductase M1 (RRM1))
    抗原表位
    • 15
    • 14
    • 9
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 74
    • 28
    • 16
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 69
    • 7
    克隆类型
    • 60
    • 16
    多克隆
    标记
    • 34
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This RRM1 antibody is un-conjugated
    应用范围
    • 41
    • 27
    • 13
    • 13
    • 11
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to RRM1 (ribonucleotide reductase M1)
    RRM1 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human RRM1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product RRM1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: NIH-3T3 , Raw264.7 , C2C12

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.49 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    RRM1 (Ribonucleotide Reductase M1 (RRM1))
    别名
    ribonucleotide reductase M1 (RRM1 产品)
    别名
    CG5371 antibody, DmRNR1 antibody, Dmel\\CG5371 antibody, RNR1 antibody, RnrM1 antibody, RntL antibody, l(2)k06709 antibody, XRRM1 antibody, R1 antibody, RIR1 antibody, RR1 antibody, CHUNP6866 antibody, cb396 antibody, cb838 antibody, r1 antibody, sb:cb548 antibody, wu:fb39b07 antibody, wu:fi14b02 antibody, wu:fk95f07 antibody, ribonucleotide reductase catalytic subunit M1 antibody, Ribonucleoside diphosphate reductase large subunit antibody, ribonucleoside-diphosphate reductase large subunit antibody, ribonucleotide reductase M1 L homeolog antibody, ribonucleotide reductase M1 antibody, ribonucleotide reductase M1 polypeptide antibody, RRM1 antibody, RnrL antibody, LOC100472317 antibody, rrm1 antibody, rrm1.L antibody, Rrm1 antibody
    背景
    This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

    Cellular Localization: Cytoplasm
    分子量
    90 kDa
    基因ID
    6240
    UniProt
    P23921
    途径
    Positive Regulation of Endopeptidase Activity
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