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Recombinant RRM1 抗体 (AA 700-800)

The 兔 单克隆 anti-RRM1 antibody (Clone RRM1-4372R) (ABIN7876549) specifically detects RRM1 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7876549
发货至: 中国
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Quick Overview for Recombinant RRM1 抗体 (AA 700-800) (ABIN7876549)

抗原

See all RRM1 抗体
RRM1 (Ribonucleotide Reductase M1 (RRM1))

抗体类型

Recombinant Antibody

适用

  • 101
  • 43
  • 31
  • 10
  • 8
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1

宿主

  • 98
  • 8

克隆类型

  • 73
  • 33
单克隆

标记

  • 52
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RRM1 antibody is un-conjugated

应用范围

  • 64
  • 29
  • 26
  • 22
  • 15
  • 13
  • 13
  • 8
  • 8
  • 8
  • 4
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

RRM1-4372R
  • 抗原表位

    • 15
    • 11
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 700-800

    原理

    RRM1 Antibody / Ribonucleotide Reductase M1 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 700-800 of human RRM1 was used as the immunogen for the RRM1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the RRM1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the RRM1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    RRM1 (Ribonucleotide Reductase M1 (RRM1))

    别名

    RRM1

    背景

    Ribonucleotide reductase M1 polypeptide (RRM1) is one of two non-identical subunits for ribonucleoside-diphosphate reductase, an enzyme which catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RRM1 is present throughout the cell division cycle but downregulated in quiescent cells. RRM1 is involved in carcinogenesis, tumor progression, and the response of non-small-cell lung cancer (NSCLC) to chemotherapy.

    UniProt

    P23921

    途径

    Positive Regulation of Endopeptidase Activity
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