RASGRP2 抗体 (AA 7-34)
Our Local Distributor
北京 101111
Quick Overview for RASGRP2 抗体 (AA 7-34) (ABIN7876487)
抗原
See all RASGRP2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 7-34
-
原理
- CalDAG-GEFI Antibody / RASGRP2
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 7-34 from the human protein was used as the immunogen for the CalDAG-GEFI antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- The stated application concentrations are suggested starting points. Titration of the CalDAG-GEFI antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the CalDAG-GEFI antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))
-
别名
- CalDAG-GEFI
-
背景
- The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.
-
UniProt
- Q7LDG7
-
途径
- TCR Signaling
抗原
-