PRELP 抗体 (AA 69-353)
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Quick Overview for PRELP 抗体 (AA 69-353) (ABIN7876441)
抗原
See all PRELP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 69-353
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原理
- Prolargin Antibody / PRELP
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids I69-R353) was used as the immunogen for the Prolargin antibody.
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亚型
- IgG
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anti-Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP) (AA 257-286), (C-Term) antibody
PRELP 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18591 unconjugated
anti-Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP) (AA 1-382) antibodyPRELP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP) (AA 119-148) antibodyPRELP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB18590 unconjugated
anti-Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP) antibodyPRELP 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP) (AA 281-365) antibodyPRELP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H1 unconjugated
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应用备注
- Optimal dilution of the Prolargin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Prolargin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))
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别名
- Prolargin
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背景
- Prolargin is a protein that in humans is encoded by the PRELP gene. The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.
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UniProt
- P51888
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途径
- Glycosaminoglycan Metabolic Process
抗原
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