LTB 抗体 (AA 68-306)
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Quick Overview for LTB 抗体 (AA 68-306) (ABIN7876397)
抗原
See all LTB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 68-306
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原理
- Lymphotoxin beta Antibody / Ltb
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived mouse recombinant protein (amino acids R68-G306) was used as the immunogen for the Lymphotoxin beta antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Lymphotoxin beta antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Lymphotoxin beta antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
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别名
- Lymphotoxin beta
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背景
- Lymphotoxin-beta (LT-beta) also known as tumor necrosis factor C (TNF-C) is a protein that in humans is encoded by the LTB gene. Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
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UniProt
- P41155
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途径
- NF-kappaB Signaling
抗原
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