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NPR3 抗体 (AA 67-97)

This 小鼠 多克隆 antibody specifically detects NPR3 in WB, IF 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7876388
发货至: 中国
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Quick Overview for NPR3 抗体 (AA 67-97) (ABIN7876388)

抗原

See all NPR3 抗体
NPR3 (Atrial Natriuretic Peptide Receptor 3 (NPR3))

适用

  • 58
  • 27
  • 20
  • 6
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 54
  • 10
  • 1
  • 1
小鼠

克隆类型

  • 54
  • 12
多克隆

标记

  • 34
  • 7
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This NPR3 antibody is un-conjugated

应用范围

  • 53
  • 26
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  • 13
  • 7
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  • 5
  • 3
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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 67-97

    原理

    Natriuretic peptide receptor C Antibody / NPRC

    免疫原

    A portion of amino acids 67-97 from the human protein was used as the immunogen for the Natriuretic peptide receptor C antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the Natriuretic peptide receptor C antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Natriuretic peptide receptor C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    NPR3 (Atrial Natriuretic Peptide Receptor 3 (NPR3))

    别名

    Natriuretic peptide receptor C

    背景

    Natriuretic peptide receptor C / NPRC is a receptor protein found in various tissues, including the heart, kidney, and blood vessels. Its main function is to bind to natriuretic peptides, which are hormones that help regulate blood pressure and fluid balance. When natriuretic peptides bind to Natriuretic peptide receptor C, they are degraded and their effects are blocked, leading to an increase in blood pressure. Natriuretic peptide receptor C also plays a role in the development of heart failure. Research has shown that increased levels of NPRC in the body can lead to impaired responses to natriuretic peptides, which in turn can contribute to the progression of heart failure. In addition to its role in cardiovascular health, NPRC has also been implicated in other diseases, such as obesity and diabetes. Studies have shown that NPRC levels are elevated in patients with these conditions, suggesting a potential link between Natriuretic peptide receptor C and metabolic disorders.

    UniProt

    P17342

    途径

    cAMP Metabolic Process
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