NPR3 抗体 (AA 67-97)
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Quick Overview for NPR3 抗体 (AA 67-97) (ABIN7876388)
抗原
See all NPR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 67-97
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原理
- Natriuretic peptide receptor C Antibody / NPRC
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免疫原
- A portion of amino acids 67-97 from the human protein was used as the immunogen for the Natriuretic peptide receptor C antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Natriuretic peptide receptor C antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Natriuretic peptide receptor C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- NPR3 (Atrial Natriuretic Peptide Receptor 3 (NPR3))
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别名
- Natriuretic peptide receptor C
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背景
- Natriuretic peptide receptor C / NPRC is a receptor protein found in various tissues, including the heart, kidney, and blood vessels. Its main function is to bind to natriuretic peptides, which are hormones that help regulate blood pressure and fluid balance. When natriuretic peptides bind to Natriuretic peptide receptor C, they are degraded and their effects are blocked, leading to an increase in blood pressure. Natriuretic peptide receptor C also plays a role in the development of heart failure. Research has shown that increased levels of NPRC in the body can lead to impaired responses to natriuretic peptides, which in turn can contribute to the progression of heart failure. In addition to its role in cardiovascular health, NPRC has also been implicated in other diseases, such as obesity and diabetes. Studies have shown that NPRC levels are elevated in patients with these conditions, suggesting a potential link between Natriuretic peptide receptor C and metabolic disorders.
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UniProt
- P17342
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途径
- cAMP Metabolic Process
抗原
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