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FLT3 抗体 (AA 66-993)

Name: FLT3 抗体 (AA 66-993)
SKU: ABIN7876357
Availability: OutOfStock

The 兔多克隆 anti-FLT3 antibody (ABIN7876357) specifically detects FLT3 in WB, ELISA 和 IHC (p). The antibody is reactive with 人和大鼠 samples.

产品编号 ABIN7876357

发货至: 中国

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Quick Overview for FLT3 抗体 (AA 66-993) (ABIN7876357)

抗原

See all FLT3 抗体

FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

适用

人, 大鼠

宿主

兔

克隆类型

多克隆

标记

This FLT3 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product FLT3 Primary Antibody

抗原表位
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2

2

2

1

1

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1
AA 66-993

原理

CD135 Antibody / FLT3

纯化方法

Antigen affinity purified

免疫原

Recombinant human protein (amino acids A66-S993) was used as the immunogen for the CD135 antibody.

亚型

IgG
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 930-991) antibody
FLT3 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 7B7C3 unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 62-295) antibody
FLT3 适用: 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 334-543) antibody
FLT3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 335-544) antibody
FLT3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64), (N-Term) antibody
FLT3 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB01544 unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64) antibody
FLT3 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (C-Term) antibody
FLT3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 650-750) antibody
FLT3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (PE)
FLT3 适用: 人 FACS 宿主: 小鼠 Monoclonal BV10A4 PE

anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (FITC)
FLT3 适用: 人 FACS 宿主: 小鼠 Monoclonal BV10A4 FITC

应用备注

Optimal dilution of the CD135 antibody should be determined by the researcher.

限制

仅限研究用
状态

Lyophilized

缓冲液

0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

储存条件

4 °C,-20 °C

储存方法

After reconstitution, the CD135 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
抗原

FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

别名

CD135

背景

Cluster of differentiation antigen 135 (CD135) also known as fms like tyrosine kinase 3 (FLT-3), receptor-type tyrosine-protein kinase FLT3, or fetal liver kinase-2 (Flk2) is a protein that in humans is encoded by the FLT3 gene. This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

UniProt

P36888

途径

RTK signaling