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Mre11 抗体 (pSer676) (Biotin)

This anti-Mre11 antibody is a 兔 多克隆 antibody detecting Mre11 in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN744160
发货至: 中国

Quick Overview for Mre11 抗体 (pSer676) (Biotin) (ABIN744160)

抗原

See all Mre11 (MRE11A) 抗体
Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

适用

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宿主

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克隆类型

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多克隆

标记

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This Mre11 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    pSer676

    交叉反应

    预测反应

    Mouse,Rat,Dog

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from rat Mre11 around the phosphorylation site of Ser676

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

    别名

    Mre11

    背景

    Synonyms: Mre 11, MRE 11a, MRE 11b, MRE11 homolog 1, MRE11 meiotic recombination 11 homolog A, MRE11a, MRE11b, AT like disease, Ataxia telangiectasia disorder like, Ataxia-telangiectasia disorder-like, ATLD, DNA recombination and repair protein, Double strand break repair protein MRE11A, Double-strand break repair protein MRE11A, endo/exonuclease Mre11. HNGS1, meiotic recombination S. cerevisiae 11 homolog A, meiotic recombination 11 homolog A S. cerevisiae, meiotic recombination 11 homolog A, M mMRE11A.MRE11_RAT

    Background: Mre11 is a component of the MRN complex, which plays a critical role in double-strand break repair (DSB), DNA recombination, maintenance of telomere integrity, and meiosis. Mre11 has both single-strand endonuclease and double strand-specific 3'-5' exonuclease activities. Rad50, another component of the MRN complex, is postulated to bind to DNA ends and hold them in close proximity, thus facilitating searches for regions of sequence homology, and also possibly stimulating the activity of DNA ligases and/or restricting Mre11 activity. Mutations in Mre11 may cause breast cancer.

    基因ID

    4361

    途径

    DNA Damage Repair
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