TLR6 抗体 (AA 65-553)
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Quick Overview for TLR6 抗体 (AA 65-553) (ABIN7876282)
抗原
See all TLR6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 65-553
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原理
- Tlr6 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant mouse protein (amino acids S65-E553) was used as the immunogen for the Tlr6 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Tlr6 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Tlr6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TLR6 (Toll-Like Receptor 6 (TLR6))
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别名
- Tlr6
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背景
- Toll-like receptor 6 is a protein that in humans is encoded by the TLR6 gene. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.
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UniProt
- Q9EPW9
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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