Pleiotrophin 抗体 (AA 61-148)
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Quick Overview for Pleiotrophin 抗体 (AA 61-148) (ABIN7876106)
抗原
See all Pleiotrophin (PTN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 61-148
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原理
- HBBM Antibody / Heparin-binding brain mitogen / Pleiotrophin
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids D61-K148) was used as the immunogen for the HBBM antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PTN antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the HBBM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Pleiotrophin (PTN)
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别名
- HBBM
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背景
- Pleiotrophin (PTN), also known as heparin-binding brain mitogen (HBBM), heparin-binding growth factor 8 (HBGF-8), neurite growth-promoting factor 1 (NEGF1), heparin affinity regulatory peptide (HARP), heparin binding growth associated molecule (HB-GAM) and Osteoblast-specific factor 1 (OSF-1), is a protein that in humans is encoded by the PTN gene. PTN is the first member of a family of developmentally regulated cytokines. The PTN gene is mapped to 7q33-q34. A mutant PTN that contained only the first N-terminal 40 amino acids was a dominant negative. Pleiotrophin is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, gut and bone. Pleiotrophin binds to cell-surface nucleolin as a low affinity receptor. This binding can inhibit HIV infection.
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UniProt
- P21246
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途径
- RTK signaling
抗原
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