COPS5 抗体 (AA 6-332)
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Quick Overview for COPS5 抗体 (AA 6-332) (ABIN7875952)
抗原
See all COPS5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-332
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原理
- Zebrafish Jab1 Antibody / Jun activation domain-binding protein 1 / Cops5
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived zebrafish Jab1/COPS5 recombinant protein (amino acids I6-S332) was used as the immunogen for the Zebrafish Jab1 antibody.
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亚型
- Ig Fraction
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应用备注
- Optimal dilution of the Zebrafish Jab1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Jab1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))
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别名
- Jab1
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背景
- COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis), also known as COPS5 or JAB1, is a gene conserved from humans to Saccharomyces cerevisiae. It is a member of the MOV34 family. COPS5 is mapped to 8q13.1. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. COPS5 can interact with the cytoplasmic domain of the beta-2 subunit of the alpha-L/beta-2 integrin LFA1, and it is the only protein demonstrated to interact with MIF. COPS5, VHL, and TRC8 proteins appear to be linked both physically and functionally, and all 3 may participate in the development of kidney cancer. In addition to that, COPS5 is an essential cofactor for the apoptotic function of E2F1.
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UniProt
- Q6PC30
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途径
- Cell Division Cycle
抗原
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