SSB 抗体 (AA 6-283)
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Quick Overview for SSB 抗体 (AA 6-283) (ABIN7875950)
抗原
See all SSB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-283
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原理
- SSB Antibody / Sjoegren syndrome type B antigen / Lupus La protein
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids D6-L283) was used as the immunogen for the SSB antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SSB antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SSB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SSB (Sjogren Syndrome Antigen B (SSB))
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别名
- SSB
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背景
- Sjogren syndrome type B antigen (SS-B) also known as Lupus La protein is a protein that in humans is encoded by the SSB gene. The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein.
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UniProt
- P05455
抗原
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