NCOR2 抗体 (AA 6-2148)
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Quick Overview for NCOR2 抗体 (AA 6-2148) (ABIN7875945)
抗原
See all NCOR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-2148
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原理
- NCOR2 Antibody / Nuclear receptor corepressor 2 / SMRT
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids Q6-H2148) was used as the immunogen for the NCOR2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the NCOR2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the NCOR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NCOR2 (Nuclear Receptor Co-Repressor 2 (NCOR2))
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别名
- NCOR2
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背景
- This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.
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UniProt
- Q9Y618
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途径
- Notch Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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