FTH1 抗体 (AA 58-180)
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北京 101111
Quick Overview for FTH1 抗体 (AA 58-180) (ABIN7875837)
抗原
See all FTH1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 58-180
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原理
- FTH Antibody / Ferritin heavy chain (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A portion of amino acids 58-180 from the human protein was used as the immunogen for the FTH antibody.
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亚型
- IgG2c, kappa
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anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-183) antibody
FTH1 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-181) antibodyFTH1 适用: Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) antibodyFTH1 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (C-Term) antibodyVerified FTH1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-183) antibodyFTH1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-100) antibodyFTH1 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-183) antibodyFTH1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal D4 unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (C-Term) antibodyFTH1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 58-180) antibodyFTH1 适用: 人, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal FTH-2081 unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 154-183), (C-Term) antibodyFTH1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21026 unconjugated
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应用备注
- Optimal dilution of the FTH antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the FTH antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))
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别名
- FTH
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背景
- Mammalian ferritins consist of 24 subunits made up of 2 types of poly-peptide chains, ferritin heavy chain and ferritin light chain, which each have unique functions. Ferritin heavy chains catalyze the first step in iron storage, the oxidationof FeI(II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe(III). The most prominent role of mammalian ferritins is to provide iron-buffering capacity to cells. In addition to iron buffering, heavy chain ferritin is also involved in the regulation of thymidine biosynthesis via increased expression of cytoplasmic serine hydroxymethyltransferase, which is a limiting factor in thymidylate synthesis in MCF-7 cells. Light chain ferritin is involved in cataracts by at least two mechanisms: hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of aging-related cataracts.
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UniProt
- P02794
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途径
- Transition Metal Ion Homeostasis
抗原
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