FTH1 抗体 (AA 58-180)
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- 抗原 See all FTH1 抗体
- FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))
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抗原表位
- AA 58-180
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FTH1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant human FTH1 protein fragment (around aa 58-180) (exact sequence is proprietary)
- 克隆位点
- FTH-2081
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product FTH1 Primary Antibody
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anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-183) antibody
FTH1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) antibodyFTH1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-181) antibodyFTH1 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (C-Term) antibodyVerified FTH1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-183) antibodyFTH1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-100) antibodyFTH1 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-183) antibodyFTH1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D4 unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (C-Term) antibodyFTH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) antibodyFTH1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Ferritin, Heavy Polypeptide 1 (FTH1) (AA 1-182) antibodyFTH1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
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- 应用备注
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Positive Control: HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Cerebellum or Testis.
Known Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))
- 别名
- FTH1 (FTH1 产品)
- 别名
- FHC antibody, FTH antibody, FTHL6 antibody, PIG15 antibody, PLIF antibody, apoferritin antibody, ferritin antibody, fhc antibody, fth antibody, fth1 antibody, fthl6 antibody, ftn-2 antibody, pig15 antibody, plif antibody, fth1b antibody, Fth antibody, HFt antibody, MFH antibody, fb06g09 antibody, hm:zeh1145 antibody, wu:fb06g09 antibody, wu:fq18c10 antibody, zeh1145 antibody, ferritin heavy chain 1 antibody, ferritin, heavy polypeptide 1 L homeolog antibody, ferritin, heavy polypeptide 1 S homeolog antibody, ferritin heavy polypeptide 1 antibody, ferritin, heavy polypeptide 1a antibody, ferritin antibody, ferritin, heavy polypeptide 1 antibody, tudor domain containing 9 antibody, ferritin, heavy polypeptide 1 a antibody, FTH1 antibody, fth1.L antibody, fth1.S antibody, Fth1 antibody, fth1a antibody, EAMY_RS19690 antibody, fth1 antibody, TDRD9 antibody
- 背景
- Mammalian ferritins consist of 24 subunits made up of 2 types of poly-peptide chains, ferritin heavy chain and ferritin light chain, which each have unique functions. Ferritin heavy chains catalyze the first step in iron storage, the oxidationof FeI(II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe(III). The most prominent role of mammalian ferritins is to provide iron-buffering capacity to cells. In addition to iron buffering, heavy chain ferritin is also involved in the regulation of thymidine biosynthesis via increased expression of cytoplasmic serine hydroxymethyltransferase, which is a limiting factor in thymidylate synthesis in MCF-7 cells. Light chain ferritin is involved in cataracts by at least two mechanisms: hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of aging-related cataracts.
- 分子量
- 21kDa
- 基因ID
- 2495
- UniProt
- P02794
- 途径
- Transition Metal Ion Homeostasis
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