LDHD 抗体 (AA 56-498)
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Quick Overview for LDHD 抗体 (AA 56-498) (ABIN7875771)
抗原
See all LDHD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 56-498
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原理
- LDHD Antibody / D-lactate dehydrogenase
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (amino acids R56-Q498) was used as the immunogen for the LDHD antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the LDHD antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the LDHD antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- LDHD (Lactate Dehydrogenase D (LDHD))
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别名
- LDHD
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背景
- Two naturally occurring forms of lactate dehydrogenase with similar but unique substrate specificities have been isolated in lower organisms including invertebrates, fungi, and prokaryotes. These dehydrogenase enzymes are L-lactate dehydrogenase and D-lactate dehydrogenase (LDHD) that are specific to the L and D isomers of lactate, respectively (PMID: 12127981). In lactic acid bacteria, LDHD plays a key role in anaerobic energy metabolism (PMID: 497162). Despite the identification of D-lactate and other D-2-hydroxyacids in prokaryotes, and the obvious connections and similarities to vertebrate metabolic pathways, very few mammalian D-2-hydroxyacid dehydrogenases have been found. LDHD has 2 isoforms with the molecular weight of 52 and 54 kDa, and can be detected as 45-54 kDa.
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UniProt
- Q86WU2
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途径
- Ribonucleoside Biosynthetic Process
抗原
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