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Recombinant ACTN2 抗体 (AA 557-692)

This 兔 单克隆 antibody specifically detects ACTN2 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7875731
发货至: 中国
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Quick Overview for Recombinant ACTN2 抗体 (AA 557-692) (ABIN7875731)

抗原

See all ACTN2 抗体
ACTN2 (Actinin, alpha 2 (ACTN2))

抗体类型

Recombinant Antibody

适用

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宿主

  • 102
  • 51

克隆类型

  • 86
  • 67
单克隆

标记

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This ACTN2 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

ACTN2-7039R
  • 抗原表位

    • 51
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    • 9
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    AA 557-692

    原理

    Recombinant ACTN2 Antibody / Alpha Actinin 2 / Sarcomeric Alpha Actinin

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 557-692 from the human protein was used as the immunogen for the recombinant ACTN2 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the recombinant ACTN2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant ACTN2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    ACTN2 (Actinin, alpha 2 (ACTN2))

    别名

    ACTN2

    背景

    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

    UniProt

    P35609

    途径

    Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
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