APLP1 抗体 (AA 55-566)
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Quick Overview for APLP1 抗体 (AA 55-566) (ABIN7875691)
抗原
See all APLP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 55-566
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原理
- APLP1 Antibody / Amyloid beta precursor like protein 1
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids Q55-Q566) was used as the immunogen for the APLP1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the APLP1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the APLP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
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别名
- APLP1
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背景
- Amyloid-precursor-like protein 1 (APLP1) is a membrane-associated glycoprotein, whose gene is homologous to the APP gene, which has been shown to be involved in the pathogenesis of Alzheimer's disease. APLP1 is predominantly expressed in brain, particularly in the cerebral cortex postsynaptic absorbance. The human gene has been mapped to chromosomal region 19q13.1. The gene is 11.8 kb long and contains 17 exons. APLP1 has been considered a candidate gene for CNF. All exon regions of the gene were amplified by the polymerase chain reaction and sequenced from DNA of CNF patients. No differences were observed between CNF patients and controls, suggesting that mutations in APLP1 are not involved in the etiology of CNF.
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UniProt
- P51693
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途径
- cAMP Metabolic Process
抗原
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