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APLP1 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects APLP1 in WB, IHC, FACS 和 ICC. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN3043786
发货至: 中国
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Quick Overview for APLP1 抗体 (N-Term) (ABIN3043786)

抗原

See all APLP1 抗体
APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

适用

  • 67
  • 67
  • 49
  • 5
  • 4
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 80
  • 2

克隆类型

  • 81
  • 1
多克隆

标记

  • 20
  • 6
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This APLP1 antibody is un-conjugated

应用范围

  • 44
  • 29
  • 17
  • 16
  • 13
  • 13
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
  • 抗原表位

    • 22
    • 15
    • 13
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    Anti-APLP1 Antibody

    序列

    RRCLRDPQRV LEYCRQMYPE LQIARVEQAT Q

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse sequence by three amino acids.

    产品特性

    Anti-APLP1 Antibody. Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human APLP1, different from the related mouse sequence by three amino acids.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, HumanWestern blot, 0.1-0.5 μg/mL, Human, RatImmunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human Immunocytochemistry, 0.5-1 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

    别名

    APLP1

    背景

    Background: Amyloid-precursor-like protein 1 (APLP1) is a membrane-associated glycoprotein, whose gene is homologous to the APP gene, which has been shown to be involved in the pathogenesis of Alzheimer's disease. APLP1 is predominantly expressed in brain, particularly in the cerebral cortex postsynaptic density. The human gene has been mapped to chromosomal region 19q13.1. The gene is 11.8 kb long and contains 17 exons. APLP1 has been considered a candidate gene for CNF. All exon regions of the gene were amplified by the polymerase chain reaction and sequenced from DNA of CNF patients. No differences were observed between CNF patients and controls, suggesting that mutations in APLP1 are not involved in the etiology of CNF.

    Gene Full Name: amyloid beta precursor like protein 1

    分子量

    85 kDa

    基因ID

    333

    UniProt

    P51693

    途径

    cAMP Metabolic Process
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