GLUD1 / GLUD2 (AA 54-553) 抗体
The 兔 多克隆 anti-GLUD1 / GLUD2 antibody (ABIN7875655) specifically detects GLUD1 / GLUD2 in ELISA, WB, IF, FACS 和 IHC (p).
The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7875655
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for GLUD1 / GLUD2 (AA 54-553) 抗体 (ABIN7875655)
抗原
GLUD1 / GLUD2
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- AA 54-553
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原理
- GLUD1/2 Antibody / GDH1/2
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids S54-A553) was used as the immunogen for the GLUD1/2 antibody.
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亚型
- IgG
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anti-GLUD1 / GLUD2 (AA 54-553) antibody
适用: 人, 小鼠, 大鼠 ELISA, WB, IF, IHC, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-GLUD1 / GLUD2 (Internal Region) antibodyVerified 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal dilution of the GLUD1/2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the GLUD1/2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- GLUD1 / GLUD2
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别名
- GLUD1/2
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背景
- This gene encodes Glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.
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UniProt
- P00367
抗原
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