GLUD1 / GLUD2 (AA 54-553) 抗体 (HRP)
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Quick Overview for GLUD1 / GLUD2 (AA 54-553) 抗体 (HRP) (ABIN7993582)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 54-553
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原理
- Anti-GLUD1/2 Antibody HRP Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GLUD1/2 recombinant protein (Position: S54-A553).
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亚型
- IgG
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anti-GLUD1 / GLUD2 (AA 54-553) antibody
适用: 人, 小鼠, 大鼠 FACS, ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-GLUD1 / GLUD2 (Internal Region) antibodyVerified 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- GLUD1 / GLUD2
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别名
- GLUD1/2
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背景
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Background: This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.
Gene Full Name: glutamate dehydrogenase 1/2
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基因ID
- 2746, 2747
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UniProt
- P00367
抗原
-
