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Occludin 抗体 (AA 54-270)

This 兔 多克隆 antibody specifically detects Occludin in WB, ELISA, FACS, IF 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7875650
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for Occludin 抗体 (AA 54-270) (ABIN7875650)

抗原

See all Occludin (OCLN) 抗体
Occludin (OCLN)

适用

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宿主

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克隆类型

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多克隆

标记

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This Occludin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 54-270

    原理

    OCLN Antibody / Occludin

    纯化方法

    Affinity purified

    免疫原

    Recombinant human protein (amino acids H54-K270) was used as the immunogen for the OCLN antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the OCLN antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the OCLN antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Occludin (OCLN)

    别名

    OCLN

    背景

    Occludin is an integral membrane protein that is located at tight junctions. It is a member of a family of proteins containing the highly conserved Marvel domain, which contains 4 transmembrane-helix regions. This gene is mapped to 5q13.2. Occludin regulates TGF-beta receptor type I localization for efficient TGF-beta-dependent dissolution of tight junctions during epithelial-mesenchymal transitions. Human Occludin is an essential hepatitis C virus (HCV) cell entry factor that is able to render murine cells infectable with HCV glycoproteins. It has been found that occludin is involved in cell migration and functions to recruit active PI3 kinase to the leading edge, resulting in RAC1 activation and formation of lamellipodia.

    UniProt

    Q16625

    途径

    Cell-Cell Junction Organization, Hepatitis C
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