Occludin 抗体 (AA 54-270)
Our Local Distributor
北京 101111
Quick Overview for Occludin 抗体 (AA 54-270) (ABIN7875650)
抗原
See all Occludin (OCLN) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 54-270
-
原理
- OCLN Antibody / Occludin
-
纯化方法
- Affinity purified
-
免疫原
- Recombinant human protein (amino acids H54-K270) was used as the immunogen for the OCLN antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal dilution of the OCLN antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the OCLN antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- Occludin (OCLN)
-
别名
- OCLN
-
背景
- Occludin is an integral membrane protein that is located at tight junctions. It is a member of a family of proteins containing the highly conserved Marvel domain, which contains 4 transmembrane-helix regions. This gene is mapped to 5q13.2. Occludin regulates TGF-beta receptor type I localization for efficient TGF-beta-dependent dissolution of tight junctions during epithelial-mesenchymal transitions. Human Occludin is an essential hepatitis C virus (HCV) cell entry factor that is able to render murine cells infectable with HCV glycoproteins. It has been found that occludin is involved in cell migration and functions to recruit active PI3 kinase to the leading edge, resulting in RAC1 activation and formation of lamellipodia.
-
UniProt
- Q16625
-
途径
- Cell-Cell Junction Organization, Hepatitis C
抗原
-