LHCGR 抗体 (AA 51-708)
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Quick Overview for LHCGR 抗体 (AA 51-708) (ABIN7875523)
抗原
See all LHCGR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-708
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原理
- Zebrafish Lhcgr Antibody / Lutropin-choriogonadotropic hormone receptor
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纯化方法
- Antigen affinity chromatography
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免疫原
- E. coli-derived zebrafish Lhcgr recombinant protein (amino acids V51-V708) was used as the immunogen for the Zebrafish Lhcgr antibody.
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亚型
- Ig Fraction
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anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (C-Term) antibody
LHCGR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) antibodyLHCGR 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8G9A2 unconjugated
anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (AA 27-363) antibodyLHCGR 适用: 人 WB, IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (AA 201-300) antibodyLHCGR 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (C-Term) antibodyVerified LHCGR 适用: 人 IF, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (AA 622-699) antibodyLHCGR 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (AA 127-143), (N-Term) antibodyLHCGR 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (C-Term) antibodyLHCGR 适用: 人, 大鼠, 小鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (Internal Region) antibodyLHCGR 适用: 人, 小鼠 WB, IF, ELISA, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (AA 70-410) antibodyLHCGR 适用: 人 IF, FACS 宿主: 小鼠 Monoclonal LHCGR-1415 unconjugated
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应用备注
- Optimal dilution of the Zebrafish Lhcgr antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Lhcgr antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
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别名
- Lhcgr
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背景
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Luteinizing hormone/choriogonadotropin receptor (Lhcgr) is a G protein-coupled receptor that mediates the actions of luteinizing hormone (LH) and chorionic gonadotropin (CG). In zebrafish (Danio rerio), Lhcgr plays a crucial role in gonadal development and function, including steroidogenesis, oocyte maturation, and ovulation.
Zebrafish lhcgr is primarily expressed in the gonads, where it facilitates LH signaling necessary for reproductive maturation and fertility. Activation of Lhcgr triggers downstream signaling cascades, including cAMP/PKA pathways, leading to the production of sex steroids such as estradiol and testosterone. Functional studies in zebrafish have shown that Lhcgr is essential for proper follicular development and ovulation in females, and for Leydig cell function in males.
As a conserved reproductive hormone receptor, zebrafish Lhcgr is a valuable model for investigating vertebrate reproductive endocrinology, hormone receptor signaling, and the genetic basis of fertility and gonadal disorders.
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UniProt
- Q6TCF8
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途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
抗原
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