PRP19 抗体 (AA 51-359)
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Quick Overview for PRP19 抗体 (AA 51-359) (ABIN7875518)
抗原
See all PRP19 (PRPF19) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-359
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原理
- SNEV Antibody / PRP19 / NMP200
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids Q51-H359) was used as the immunogen for the SNEV antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SNEV antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SNEV antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PRP19 (PRPF19) (Pre-mRNA Processing Factor 19 (PRPF19))
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别名
- SNEV
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背景
- Pre-mRNA-processing factor 19, also called PRP19, SNEV (Senescence evasion factor) and NMP200 (Nuclear matrix protein 200), is a protein that in humans is encoded by the PRPF19 gene. Enables identical protein binding activity and ubiquitin-ubiquitin ligase activity. Involved in several processes, including DNA damage checkpoint signaling, cellular protein metabolic process, and mRNA splicing, via spliceosome. Acts upstream of or within protein polyubiquitination. Located in cytoplasm, nuclear speck, and site of double-strand break. Part of Prp19 complex and U2-type catalytic step 2 spliceosome. Colocalizes with DNA replication factor A complex.
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UniProt
- Q9UMS4
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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