DNMT1 抗体 (AA 509-1577)
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Quick Overview for DNMT1 抗体 (AA 509-1577) (ABIN7875507)
抗原
See all DNMT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 509-1577
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原理
- DNA methyltransferase 1 Antibody / Dnmt1
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant mouse protein (amino acids Q509-Q1577) was used as the immunogen for the DNA methyltransferase 1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the DNA methyltransferase 1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the DNA methyltransferase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
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别名
- DNA methyltransferase 1
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背景
- DNA (cytosine-5)-methyltransferase 1 is an enzyme that in humans is encoded by the DNMT1 gene. This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.
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UniProt
- P13864
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途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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