VAV3 抗体 (AA 507-702)
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Quick Overview for VAV3 抗体 (AA 507-702) (ABIN7875501)
抗原
See all VAV3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 507-702
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原理
- VAV3 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids D507-E702) was used as the immunogen for the VAV3 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the VAV3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the VAV3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- VAV3 (Vav 3 Oncogene (VAV3))
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别名
- VAV3
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背景
- Guanine nucleotide exchange factor VAV3 is a protein that in humans is encoded by the VAV3 gene. This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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UniProt
- Q9UKW4
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途径
- Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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