FLT3 抗体 (AA 500-800)
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Quick Overview for FLT3 抗体 (AA 500-800) (ABIN7875479)
抗原
See all FLT3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 500-800
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原理
- CD135 Antibody / FLT3 (azide and preservative free)
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纯化方法
- Protein G affinity
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免疫原
- A portion of amino acids 500-800 from human FLT3 protein was used as the immunogen for the CD135 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the CD135 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the CD135 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
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别名
- CD135
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背景
- Stem cell tyrosine kinase (STK-1) has been cloned from a CD34+ hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of Mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85 % identity to Flt-3/Flk-2. STK-1 is a member of the type III receptor tyrosine kinase family that includes Kit (steel factor receptor), Fms and PDGF. STK-1 expression in blood and marrow is restricted to CD34+ cells, a population greatly enriched for hematopoietic stem/progenitor cells. STK-1 antiserum recognizes two polypeptides in these cells. The Mouse homolog of STK-1, designated Flt-3/Flk-2, is expressed at high levels in hematopoietic cells and also in neural, gonadal, hepatic and placental tissues. It has been suggested that STK-1 and its murine homolog Flt-3/Flk-2 may function as growth factor receptors on hematopoietic stem and/or progenitor cells.
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UniProt
- P36888
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途径
- RTK signaling
抗原
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