IRF3 抗体 (AA 5-422)
Our Local Distributor
北京 101111
Quick Overview for IRF3 抗体 (AA 5-422) (ABIN7875310)
抗原
See all IRF3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 5-422
-
原理
- IRF3 Antibody
-
纯化方法
- Affinity purified
-
免疫原
- Recombinant human protein (amino acids K5-Q422) was used as the immunogen for the IRF3 antibody.
-
亚型
- IgG
-
-
anti-Interferon Regulatory Factor 3 (IRF3) (pSer396) antibody
IRF3 适用: 人 WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-260) antibodyIRF3 适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-452) antibodyIRF3 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 3C8 unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 51-150) antibodyIRF3 适用: 人 WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-360) antibodyIRF3 适用: 人 WB, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 5-422) antibodyIRF3 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) antibodyIRF3 适用: 人 WB, IF, IHC (p), IHC (fro) 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
anti-Interferon Regulatory Factor 3 (IRF3) antibodyIRF3 适用: 人 WB, FACS, ICC, IP, DB 宿主: 小鼠 Monoclonal IRF35I218 unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (pSer386) antibodyIRF3 适用: 人, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 3 (IRF3) (AA 1-452) antibodyIRF3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal dilution of the IRF3 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the IRF3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- IRF3 (Interferon Regulatory Factor 3 (IRF3))
-
别名
- IRF3
-
背景
- IRF3 (interferon regulatory factor 3) is a member of the interferon regulatory transcription factor (IRF) family. The IRF3 gene is mapped on 19q13.33. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. IRF3 plays an important role in the innate immune system's response to viral infection. Aggregated MAVS have been found to activate IRF3 dimerization. Although IRF3 increased transcriptional activity from an ISRE-containing promoter, expression of IRF3 as a Gal4 fusion protein did not activate expression of a chloramphenicol acetyltransferase (CAT) reporter gene containing repeats of the Gal4-binding sites. Translocation of IRF3 was accompanied by an increase in serine and threonine phosphorylation. The transcriptional activators CREBBP and EP300 coimmunoprecipitated with IRF3 only subsequent to viral infection, and the authors stated that these are also subunits of DRAF1.
-
UniProt
- Q14653
-
途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
抗原
-
