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CD276 抗体 (AA 493-522)

The 兔 多克隆 anti-CD276 antibody (ABIN7875265) specifically detects CD276 in WB, FACS, IHC (p) 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7875265
发货至: 中国
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Quick Overview for CD276 抗体 (AA 493-522) (ABIN7875265)

抗原

See all CD276 抗体
CD276

适用

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宿主

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克隆类型

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  • 1
多克隆

标记

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This CD276 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

    • 20
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    AA 493-522

    原理

    CD276 Antibody / B7-H3

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 493-522 from the human protein was used as the immunogen for the CD276 antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the CD276 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the CD276 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CD276

    别名

    CD276

    背景

    May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling. [UniProt]

    UniProt

    Q5ZPR3

    途径

    Cancer Immune Checkpoints
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