IDE 抗体 (AA 464-735)
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北京 101111
Quick Overview for IDE 抗体 (AA 464-735) (ABIN7875138)
抗原
See all IDE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 464-735
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原理
- Zebrafish Ide Antibody / Insulin degrading enzyme
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived zebrafish Ide recombinant protein (amino acids F464-K735) was used as the immunogen for the Zebrafish Ide antibody.
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亚型
- Ig Fraction
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anti-Insulin-Degrading Enzyme (IDE) (AA 491-590) antibody
IDE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (AA 753-973) antibodyIDE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (AA 1-250) antibodyIDE 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) antibodyKD Validated IDE 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB6210 unconjugated Recombinant Antibody
anti-Insulin-Degrading Enzyme (IDE) (AA 485-756) antibodyIDE 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) antibodyIDE 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-Insulin-Degrading Enzyme (IDE) (Internal Region) antibodyVerified IDE 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (AA 920-1019) antibodyIDE 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (N-Term) antibodyIDE 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Zebrafish Ide antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Ide antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- IDE (Insulin-Degrading Enzyme (IDE))
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别名
- Ide
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背景
- Insulin-degrading enzyme, also known as IDE, is a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signaling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causative for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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途径
- SARS-CoV-2 Protein Interactome
抗原
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