LYVE1 抗体 (AA 46-77)
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北京 101111
Quick Overview for LYVE1 抗体 (AA 46-77) (ABIN7875125)
抗原
See all LYVE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 46-77
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原理
- LYVE1 Antibody / XLKD1
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纯化方法
- SAS precipitation
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免疫原
- A portion of amino acids 46-77 from the human protein was used as the immunogen for the LYVE1 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the LYVE1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the LYVE1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
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别名
- LYVE1
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背景
- One of the key groups of molecules regulating leukocyte and tumour cell migration is the glycosaminoglycan hyaluronan (HA). In inflammation, the exit of leukocytes across vascular endothelium to the underlying tissues involves interactions with cell surface lectin-like receptors on the leukocytes that bind HA on the lumenal surface of the endothelium. During normal tissue homeostasis and after tissue injury, HA is mobilized from these sites through lymphatic vessels to the lymph nodes where it is degraded before entering the circulation for rapid uptake by the liver. Lymphatic vessel endothelial hyaluronan receptor (LYVE)-1 is a major receptor for HA on the lymph vessel wall. LYVE-1 is expressed primarily on lymphatic vessel endothelium and is likely to be involved in regulating the traffic of leucocytes and tumour cells to lymph nodes.
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UniProt
- Q9Y5Y7
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途径
- Glycosaminoglycan Metabolic Process
抗原
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