Seryl-tRNA Synthetase (SARS) (AA 46-518) 抗体
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Quick Overview for Seryl-tRNA Synthetase (SARS) (AA 46-518) 抗体 (ABIN7875122)
抗原
See all Seryl-tRNA Synthetase (SARS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 46-518
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原理
- SerRS Antibody / Seryl-tRNA synthetase / SARS2
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids E46-S518) was used as the immunogen for the SerRS antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SerRS antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SerRS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Seryl-tRNA Synthetase (SARS)
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别名
- SerRS
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背景
- Seryl-tRNA synthetase, mitochondrial is an enzyme that in humans is encoded by the SARS2 gene. This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene.
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UniProt
- Q9NP81
抗原
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