TNNT3 抗体 (AA 45-251)
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北京 101111
Quick Overview for TNNT3 抗体 (AA 45-251) (ABIN7875059)
抗原
See all TNNT3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 45-251
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原理
- TNNT3 Antibody
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纯化方法
- Affinity purified
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免疫原
- A human recombinant protein (amino acids A45-K251) was used as the immunogen for the TNNT3 antibody.
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亚型
- IgG
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anti-Fast Skeletal Troponin T (TNNT3) (AA 161-258) antibody
TNNT3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F12 unconjugated
anti-Fast Skeletal Troponin T (TNNT3) (AA 161-258) antibodyTNNT3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-Fast Skeletal Troponin T (TNNT3) antibodyTNNT3 适用: 人, 小鸡, Quail WB, ELISA, IHC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal T1-61 unconjugated
anti-Fast Skeletal Troponin T (TNNT3) (C-Term) antibodyTNNT3 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fast Skeletal Troponin T (TNNT3) (AA 161-258) antibodyTNNT3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Fast Skeletal Troponin T (TNNT3) (AA 1-250) antibodyTNNT3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Fast Skeletal Troponin T (TNNT3) (C-Term) antibodyVerified TNNT3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Fast Skeletal Troponin T (TNNT3) (C-Term) antibody (Biotin)Verified TNNT3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal Biotin
anti-Fast Skeletal Troponin T (TNNT3) (AA 31-80) antibodyTNNT3 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 小鸡, Cow, 马, 犬, 山羊, 斑马鱼, 猴, Pig, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Fast Skeletal Troponin T (TNNT3) (C-Term) antibodyTNNT3 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 马, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the TNNT3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the TNNT3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TNNT3 (Fast Skeletal Troponin T (TNNT3))
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别名
- TNNT3
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背景
- Fast skeletal muscle troponin T (fTnT) is a protein that in humans is encoded by the TNNT3 gene. It is mapped to 11p15.5. The binding of Ca(2+) to the trimeric troponin complex initiates the process of muscle contraction. Increased Ca(2+) concentrations produce a conformational change in the troponin complex that is transmitted to tropomyosin dimers situated along actin filaments. The altered conformation permits increased interaction between a myosin head and an actin filament which, ultimately, produces a muscle contraction. The troponin complex has protein subunits C, I, and T. Subunit C binds Ca(2+) and subunit I binds to actin and inhibits actin-myosin interaction. Subunit T binds the troponin complex to the tropomyosin complex and is also required for Ca(2+)-mediated activation of actomyosin ATPase activity. There are 3 different troponin T genes that encode tissue-specific isoforms of subunit T for fast skeletal-, slow skeletal-, and cardiac-muscle. This gene encodes fast skeletal troponin T protein, also known as troponin T type 3. Alternative splicing results in multiple transcript variants encoding additional distinct troponin T type 3 isoforms. A developmentally regulated switch between fetal/neonatal and adult troponin T type 3 isoforms occurs. Additional splice variants have been described but their biological validity has not been established. Mutations in this gene may cause distal arthrogryposis multiplex congenita type 2B (DA2B).
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UniProt
- P45378
抗原
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