Involucrin 抗体 (AA 421-568)
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Quick Overview for Involucrin 抗体 (AA 421-568) (ABIN7874933)
抗原
See all Involucrin (IVL) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 421-568
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原理
- Involucrin Antibody
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纯化方法
- Protein G affinity chromatography
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免疫原
- Purified involucrin from human keratinocytes was used as the immunogen for this Involucrin antibody. Its epitope maps between amino acids 421-568 of human involucrin.
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亚型
- IgG1, kappa
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anti-Involucrin (IVL) (AA 461-551) antibody
IVL 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Involucrin (IVL) antibodyIVL 适用: 人 IHC, WB 宿主: 兔 Monoclonal unconjugated
anti-Involucrin (IVL) (AA 65-180) antibodyIVL 适用: 人 ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Involucrin (IVL) (AA 301-460) antibodyIVL 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Involucrin (IVL) antibodyIVL 适用: 人, 小鼠 IHC, WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Involucrin (IVL) (AA 24-118) antibodyIVL 适用: 人 IHC, WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Involucrin (IVL) antibodyIVL 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Involucrin (IVL) (AA 36-152) antibodyIVL 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Involucrin (IVL) antibodyIVL 适用: 人, 犬, Pig, Gorilla, Owl Monkey IHC, WB 宿主: 小鼠 Monoclonal rIVRN-827 unconjugated Recombinant Antibody
anti-Involucrin (IVL) antibodyIVL 适用: 人, 犬, Pig, Gorilla, Owl Monkey IHC 宿主: 小鼠 Monoclonal SY5 unconjugated
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应用备注
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The optimal dilution of the Involucrin antibody for each application should be determined by the researcher.
1. Staining of formalin-fixed tissues is enhanced by digestion with Trypsin or Protease XXV at 1 mg/mL PBS for 5 min at 37oC. Enzyme digestion is better than citrate buffer based epitope unmasking.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Involucrin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Involucrin (IVL)
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别名
- Involucrin
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背景
- Involucrin is expressed in a range of stratified squamous epithelia, including the cornea, which lacks a distinct cornified layer. In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures, all cells that have left the basal layer express it. Involucrin expression is altered in pathological conditions: in psoriasis and other benign epidermal hyperplasias, involucrin expression begins closer to the basal layer than normal, expression is abnormal in squamous cell carcinomas and premalignant lesions, and is reduced in severe dysplasias of the larynx and cervix.
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UniProt
- P07476
抗原
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