Cathepsin B 抗体 (AA 42-339)
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Quick Overview for Cathepsin B 抗体 (AA 42-339) (ABIN7874922)
抗原
See all Cathepsin B (CTSB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 42-339
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原理
- CTSB Antibody / Cathepsin B
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids Q42-K339) was used as the immunogen for the CTSB antibody.
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亚型
- IgG
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anti-Cathepsin B (CTSB) (AA 1-339) antibody
CTSB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 251-339) antibodyCTSB 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 82-333) antibodyCTSB 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 42-339) antibodyCTSB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 1-339) antibodyCTSB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cathepsin B (CTSB) antibodyCTSB 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Cathepsin B (CTSB) antibodyKD Validated CTSB 适用: 人 WB 宿主: 兔 Monoclonal 23GB1130 unconjugated Recombinant Antibody
anti-Cathepsin B (CTSB) (AA 129-333) antibodyCTSB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 129-333) antibodyCTSB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cathepsin B (CTSB) (AA 129-333) antibodyCTSB 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the CTSB antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the CTSB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Cathepsin B (CTSB)
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别名
- CTSB
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背景
- Cathepsin B is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSB gene. And this gene is mapped to chromosome 8p22. The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. Cathepsin B was once suspected as a candidate protease participating in the conversion of beta-amyloid precursor protein into the amyloid plaques found in Alzheimer's disease patients. However, this function is now known to be mediated by BACE1 protease. It is now thought that cathepsin B can degrade beta-amyloid precursor protein into harmless fragments. Thus, it is conceivable cathepsin B may play a pivotal role in the natural defense against Alzheimer's disease. Overexpression of cathepsin B has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.
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UniProt
- P07858
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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