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CYBB 抗体 (AA 416-527)

This 兔 多克隆 antibody specifically detects CYBB in WB, ELISA 和 FACS. It exhibits reactivity toward 人.
产品编号 ABIN7874906
发货至: 中国
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Quick Overview for CYBB 抗体 (AA 416-527) (ABIN7874906)

抗原

See all CYBB 抗体
CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

适用

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宿主

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克隆类型

  • 52
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多克隆

标记

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This CYBB antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 416-527

    原理

    NOX2/gp91phox Antibody / CYBB

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids F416-H527) was used as the immunogen for the NOX2/gp91phox antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the NOX2/gp91phox antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the NOX2/gp91phox antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

    别名

    NOX2/gp91phox

    背景

    NOX2 (NADPH OXIDASE 2), also called CYBB (CYTOCHROME b(-245), BETA SUBUNIT), p91-PHOX or GP91-1, is a human gene encoding a glycoprotein. NOX2 is an essential component of phagocytic NADPH-oxidase, a membrane-bound enzyme complex that generates large quantities of microbicidal superoxide and other oxidants upon activation. It is mapped on Xp11.4. NOX2 assembled on DC phagosomes in a gp91-phox subunit-dependent manner, and that reactive oxygen species were produced in a more sustained manner in immature DC phagosomes than in macrophage phagosomes. As a major player in innate immune responses in neutrophils, NOX2 is also involved in adaptive immunity through its activity in DCs. In heart cells, physiologic stretch rapidly activates reduced-form NOX2 to produce reactive oxygen species (ROS) in a process dependent on microtubules (X-ROS signaling).

    UniProt

    P04839
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