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UBA3 抗体 (AA 415-445)

This 兔 多克隆 antibody specifically detects UBA3 in WB 和 IHC (p). It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7874882
发货至: 中国
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Quick Overview for UBA3 抗体 (AA 415-445) (ABIN7874882)

抗原

See all UBA3 抗体
UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))

适用

  • 30
  • 23
  • 14
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 32

克隆类型

  • 28
  • 4
多克隆

标记

  • 20
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This UBA3 antibody is un-conjugated

应用范围

  • 24
  • 13
  • 9
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 415-445

    原理

    UBA3 Antibody / UBE1C

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 415-445 from the human protein was used as the immunogen for the UBA3 antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the UBA3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the UBA3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))

    别名

    UBA3

    背景

    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

    UniProt

    Q8TBC4
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