UBA3 抗体 (AA 415-445)
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Quick Overview for UBA3 抗体 (AA 415-445) (ABIN7874882)
抗原
See all UBA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 415-445
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原理
- UBA3 Antibody / UBE1C
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 415-445 from the human protein was used as the immunogen for the UBA3 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the UBA3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the UBA3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))
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别名
- UBA3
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背景
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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UniProt
- Q8TBC4
抗原
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