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IKZF1 抗体 (AA 415-444)

The 兔 多克隆 anti-IKZF1 antibody (ABIN7874881) specifically detects IKZF1 in WB, FACS 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7874881
发货至: 中国
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Quick Overview for IKZF1 抗体 (AA 415-444) (ABIN7874881)

抗原

See all IKZF1 抗体
IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

适用

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宿主

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克隆类型

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多克隆

标记

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This IKZF1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 415-444

    原理

    IKAROS Antibody / IKZF1

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 415-444 from the human protein was used as the immunogen for the IKAROS antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the IKAROS antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the IKAROS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

    别名

    IKAROS

    背景

    Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs) (By similarity). [UniProt]

    UniProt

    Q13422

    途径

    Production of Molecular Mediator of Immune Response
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