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GLUD1 抗体 (AA 40-539)

The 兔 多克隆 anti-GLUD1 antibody (ABIN7874704) specifically detects GLUD1 in WB 和 IHC (p). The antibody is reactive with 斑马鱼 samples.
产品编号 ABIN7874704
发货至: 中国
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Quick Overview for GLUD1 抗体 (AA 40-539) (ABIN7874704)

抗原

See all GLUD1 抗体
GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

适用

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斑马鱼

宿主

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克隆类型

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多克隆

标记

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This GLUD1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 40-539

    原理

    Zebrafish Glud1 Antibody / Glud1a / Glud1b / Glutamate dehydrogenase

    纯化方法

    Antigen affinity chromatography

    免疫原

    An E.coli-derived zebrafish Glud1a/b recombinant protein (amino acids S40-A539) was used as the immunogen for the Zebrafish Glud1 antibody. This antibody will detect the a and b isoforms.

    亚型

    Ig Fraction
  • 应用备注

    Optimal dilution of the Zebrafish Glud1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Zebrafish Glud1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

    别名

    Glud1

    背景

    This gene encodes Glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.

    UniProt

    Q6NZ29

    途径

    Positive Regulation of Peptide Hormone Secretion, Warburg Effect
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