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NEFL 抗体 (AA 4-463)

The 兔 多克隆 anti-NEFL antibody is suitable to detect NEFL in samples from 人, 大鼠 和 小鼠. It has been validated for WB, ELISA, IF, FACS 和 IHC (p).
产品编号 ABIN7874679
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for NEFL 抗体 (AA 4-463) (ABIN7874679)

抗原

See all NEFL 抗体
NEFL (Neurofilament, Light Polypeptide (NEFL))

适用

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人, 大鼠, 小鼠

宿主

  • 86
  • 38
  • 9
  • 1
  • 1
  • 1

克隆类型

  • 72
  • 64
多克隆

标记

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  • 12
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This NEFL antibody is un-conjugated

应用范围

  • 79
  • 67
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  • 27
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  • 8
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  • 3
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 6
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    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 4-463

    原理

    Neurofilament Light Antibody / NF-L

    纯化方法

    Affinity purified

    免疫原

    A human recombinant partial protein (amino acids F4-A463) was used as the immunogen for the Neurofilament Light antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Neurofilament Light antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Neurofilament Light antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    NEFL (Neurofilament, Light Polypeptide (NEFL))

    别名

    Neurofilament Light

    背景

    Neurofilament light polypeptide (NFL), also known as neurofilament light chain, is a neurofilament protein that in humans is encoded by the NEFL gene. Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

    UniProt

    P07196
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