NEFL 抗体 (AA 4-463)
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Quick Overview for NEFL 抗体 (AA 4-463) (ABIN7874679)
抗原
See all NEFL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-463
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原理
- Neurofilament Light Antibody / NF-L
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纯化方法
- Affinity purified
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免疫原
- A human recombinant partial protein (amino acids F4-A463) was used as the immunogen for the Neurofilament Light antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Neurofilament Light antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Neurofilament Light antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NEFL (Neurofilament, Light Polypeptide (NEFL))
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别名
- Neurofilament Light
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背景
- Neurofilament light polypeptide (NFL), also known as neurofilament light chain, is a neurofilament protein that in humans is encoded by the NEFL gene. Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
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UniProt
- P07196
抗原
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