UPF3A 抗体 (AA 4-452)
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Quick Overview for UPF3A 抗体 (AA 4-452) (ABIN7874678)
抗原
See all UPF3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-452
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原理
- RENT3A Antibody / UPF3A
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids E4-E452) was used as the immunogen for the RENT3A antibody.
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亚型
- IgG
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anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 274-374) antibody
UPF3A 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2E2 unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 327-476) antibodyUPF3A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 1-443) antibodyUPF3A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 382-475) antibodyUPF3A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 359-408) antibodyUPF3A 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A) (AA 4-452) antibodyUPF3A 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the RENT3A antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the RENT3A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- UPF3A (UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A))
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别名
- RENT3A
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背景
- Regulator of nonsense transcripts 3A is a protein that in humans is encoded by the UPF3A gene. This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome 13. Several splice variants encoding different isoforms have been found for this gene.
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UniProt
- Q9H1J1
抗原
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