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UPF3A 抗体

UPF3A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7120628
发货至: 中国
  • 抗原 See all UPF3A 抗体
    UPF3A (UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A))
    适用
    人, 小鼠, 大鼠
    宿主
    • 10
    • 5
    • 1
    克隆类型
    • 14
    • 2
    多克隆
    标记
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UPF3A antibody is un-conjugated
    应用范围
    • 8
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    UPF3 regulator of nonsense transcripts homolog A(yeast)
    亚型
    IgG
    Top Product
    Discover our top product UPF3A Primary Antibody
  • 应用备注
    WB: 1:500-1:5000, IHC:1:20-1:200,IF: 1:20-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    UPF3A (UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A))
    别名
    UPF3A (UPF3A 产品)
    别名
    2600001C03Rik antibody, 4930546M19Rik antibody, RENT3A antibody, UPF3 antibody, UPF3A antibody, HUPF3A antibody, si:dkey-21o13.6 antibody, UPF3 regulator of nonsense transcripts homolog A (yeast) antibody, UPF3A, regulator of nonsense mediated mRNA decay antibody, Upf3a antibody, UPF3A antibody, upf3a antibody
    背景
    Synonyms:HUpf3, HUPF3A, RENT3A, UPF3, UPF3A Background:Involved in nonsense-mediated decay(NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex(EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex(including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. However, UPF3A is shown to be only marginally active in NMD as compared to UPF3B. Binds spliced mRNA upstream of exon-exon junctions. In vitro, weakly stimulates translation.
    分子量
    51 kDa
    基因ID
    65110
    UniProt
    Q9H1J1
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