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MADD 抗体 (AA 4-335)

The 兔 多克隆 anti-MADD antibody is suitable to detect MADD in samples from 斑马鱼. It has been validated for WB.
产品编号 ABIN7874673
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MADD 抗体 (AA 4-335) (ABIN7874673)

抗原

See all MADD 抗体
MADD (MAP-Kinase Activating Death Domain (MADD))

适用

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斑马鱼

宿主

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克隆类型

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多克隆

标记

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This MADD antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 4-335

    原理

    Zebrafish Madd Antibody / MAP kinase-activating death domain protein

    纯化方法

    Antigen affinity chromatography

    免疫原

    An E.coli-derived zebrafish Madd recombinant protein (amino acids K4-Y335) was used as the immunogen for the Zebrafish Madd antibody.

    亚型

    Ig Fraction
  • 应用备注

    Optimal dilution of the Zebrafish Madd antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Zebrafish Madd antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    MADD (MAP-Kinase Activating Death Domain (MADD))

    别名

    Madd

    背景

    MAP kinase-activating death domain protein is an enzyme that in humans is encoded by the MADD gene. Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene.

    途径

    Caspase Cascade in Apoptosis
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