MADD 抗体 (AA 751-800)
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北京 101111
Quick Overview for MADD 抗体 (AA 751-800) (ABIN1534033)
抗原
See all MADD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 751-800
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原理
- MADD Antibody
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特异性
- MADD Polyclonal Antibody detects endogenous levels of MADD protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MADD. AA range:751-800
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亚型
- IgG
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anti-MAP-Kinase Activating Death Domain (MADD) antibody
KD Validated MADD 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB110 unconjugated Recombinant Antibody
anti-MAP-Kinase Activating Death Domain (MADD) antibodyMADD 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-MAP-Kinase Activating Death Domain (MADD) (AA 1597-1647) antibodyMADD 适用: 人 IHC, IF (p) 宿主: 兔 Polyclonal unconjugated
anti-MAP-Kinase Activating Death Domain (MADD) (C-Term) antibodyMADD 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MAP-Kinase Activating Death Domain (MADD) (Internal Region) antibodyMADD 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-MAP-Kinase Activating Death Domain (MADD) (Internal Region) antibodyMADD 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-MAP-Kinase Activating Death Domain (MADD) (AA 1597-1647) antibodyMADD 适用: 人 WB, IF (p), IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MADD (MAP-Kinase Activating Death Domain (MADD))
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别名
- MADD
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背景
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Synonyms: MADD, DENN, IG20, KIAA0358, MAP kinase-activating death domain protein, Differentially expressed in normal and neoplastic cells, Insulinoma glucagonoma clone 20, Rab3 GDP/GTP exchange factor
Background: Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins.The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
Gene Name: MADD
Protein Name: MAP kinase-activating death domain protein
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分子量
- 183 kDa
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基因ID
- 8567
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OMIM
- 603584
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UniProt
- Q8WXG6
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途径
- Caspase Cascade in Apoptosis
抗原
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