MMP12 抗体 (AA 391-420)
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北京 101111
Quick Overview for MMP12 抗体 (AA 391-420) (ABIN7874614)
抗原
See all MMP12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 391-420
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原理
- MMP12 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 391-420 from the human protein were used as the immunogen for the MMP12 antibody.
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亚型
- Ig Fraction
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anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 391-420), (C-Term) antibody
MMP12 适用: 人, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB2026 unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 20-99) antibodyMMP12 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 100-286) antibodyMMP12 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 290-469) antibodyMMP12 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 294-473) antibodyMMP12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 372-463) antibodyMMP12 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 1-470) antibodyMMP12 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 109-470) antibodyMMP12 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) antibodyMMP12 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 201-300) antibodyMMP12 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the MMP12 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MMP12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
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别名
- MMP12
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背景
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP12 may be involved in tissue injury and remodeling. This protein has significant elastolytic activity. MMP12 can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, wtih small hydrophobic residues (prefereably alanine) occupying P3. The protein is found in alveolar macrophages but not in peripheral blood monocytes. MMP12 can be induced by exposure to lypopolysaccharide, and is inhibited by dexamethasone.
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UniProt
- P39900
抗原
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